Lysine has been studied for the prevention and treatment of herpes infections and cold sores. It also increases the intestinal absorption of calcium and eliminates its excretion by the kidney, suggesting that it might be helpful in osteoporosis.
Lysine has been investigated for its effects on increasing muscle mass, lowering glucose, and improving anxiety. Lysine acetylsalicylate has been used to treat pain and to detoxify the body after heroin use. Lysine clonixinate has been used to relieve migraine headaches and other painful conditions.